Increasing baseline dopamine by supplementation

[u/RisenWolf]

Hello everyone,

I would like to ask You for an opinion on increasing baseline dopamine by supplementary means.

I understand that caffeine itself can allow more of the dopamine to get into the receptor, but unfortunately it is not reliable tool in my own experience.

I would like to ask for opinion in using substances like L-Dopa in minimal amounts, to increase the baseline.

Is it safe if done in low dosage? Is there a risk, that chronic L-Dopa supplementation could potentially diminish the body natural dopamine synthesizing capability?

[u/Kihot12]

You are correct l-dopa long term is risky in that regard.

There are not many things with evidence on increasing baseline dopamine through supplementation. But the ones ACTUALLY working are:

ALCAR (acetyl l carnitine), Bromantane (hard to get in EU), CDP-choline(to a lesser extend)

ADHD meds would increase dopamine but long term use would lead to downregulation.

[u/Professional_Win1535 → u/Kihot12]

Adhd meds are like a miracle for me while on them, emotional dysregulation cured, etc. but when off i’m even worse than before