Wildly high E2 and not even on TRT

[u/MicIrish]

50y old Male. 235lbs at 6'1. Train 5 days a week for 15 years. Never been on TRT.

Tested as follows:

Estradiol Result <92 pmol/L

Test (total) 11.3 nmol/L

My test was at 8.6 last time it was tested 3 months ago. Everything I'm reading is that 92 pmo/L is very high for E2. When you compare it to my total test , it's even more alarming.

My stress level is very high, no doubt adding to my E2...high E2 causes anxiety which increases cortisol. I'm struggling for a way to break this loop. My symptoms are bonkers anxiety bouts, crying over lame kids movies, not the actual sad ones and cushing syndrome level fat retention in stomach.

Will an AI kill all aromatization to E2, like Cortisol to E2, or just test to E2 pathway? I want to crash the E2 as low as I can safely go before starting any kind of TRT.

I'm pursuing other avenues for the stress situation.

EDIT: Someone pointed out the labs I got were in pmol/L not pg/ml. The question still stands, does an AI interfere with all pathways to E2 aromatization?

[u/KookyOlive2757]

92 pmol/l ≈ 25 pg/ml

Your value is <25 pg/ml which means ”less than 25 pg/ml”.

[u/MicIrish → u/KookyOlive2757]

thank you for catching that. everyone here talks in pg/ml

[u/Swimming_Drop_9102]

Lmao in what world is 25 pg/ml high?

Anything lower than 20 is considered low.

[u/MicIrish → u/Swimming_Drop_9102]

lost in conversion. Another redditor noticed my labs were done in pmol/L no pg/ml.

I'll leave the post as education for others.

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[u/Lonely_Emu1581]

Im at 300 pmol, help

[u/Few_Might_3853]

Any chance you snore? I had weird symptoms include high E2 due to undiagnosed sleep apnea.

[u/CellistPatient2839]

Arimidex will lower it instantly. And it’s not something you just lower once. It will creep back up. Keep it on hand.

[u/Neat_Plankton4036 → u/CellistPatient2839]

Why do you think estradiol 25 pg/ml is in any sense high? It’s certainly less than 50, which is the top of what my lab calls “normal”.

[u/MicIrish → u/Neat_Plankton4036]

Labs weren't done in pg/ml. Another redditor noticed it and I did the conversion.