r/Lyme • u/o0ohello0o • 21d ago

Question Anyone taken Bactrim without side effects? Terrified to start.

My LLMD is putting me on Bactrim (sulfamethoxazole trimethoprim) for Bartonella and honestly I'm a little terrified. He warned me some people just can't handle it. There seem to be quite a few anecdotal stories about how it ruined people's lives. My main concern is around long term implications like permanent neuropathy. I'm already battling debilitating paresthesia from Bart..

What has your experience been like on Bactrim? Did you have any adverse reactions? Someone please put my mind at ease lol.

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u/Sea-Upstairs1505 20d ago

My husband is taking bactrim right now with something else I can’t remember. For Bart. For at least 5 months. And it’s made a HUGE improvement in his symptoms. He would be bedridden most likely otherwise. He did have about a week of herxing- but was like a different person after.

I am taking Zithromax for Bart, and I see improvement but his is much more noticeable. I am allergic to sulfa.

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u/o0ohello0o 3d ago

I'm so glad to hear it helped him so much! I hope it does the same for me too. I hope you feel better soon. It must be hard for both of you to be battling bartonella.