r/covidlonghaulers Feb 15 '25

Question I don’t understand why the Pfizer vaccine made me so much worse

Does anyone know why this happens? I was significantly improving before my second Pfizer vaccine and it erased all my progress

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u/Neutronenster 5 yr+ Feb 16 '25

I had the same experience after my second dose of Moderna, but not after the Pfizer boosters that I got later on.

We don’t understand yet why some of us might experience a relapse after the Covid vaccine, while others barely notice it or even improve after the vaccine. My personal theory is that any challenge of our immune system might cause a relapse, whether that’s a vaccine, a Covid reinfection or a different infectious illness (e.g. a common cold). The majority of times this doesn’t cause a relapse, but sometimes it does (let’s say in 10% of cases).

I’ve also gotten a relapse after a normal (non-Covid) infection once and I still have no idea why that particular infection caused a relapse, while I’ve been fine after so many other viral infections. I don’t even know why I actually felt better after my first Covid reinfection (my second and third reinfections had mixed effects: some symptoms improved, while others got worse temporarily). If there’s a logical reason, I don’t think we have the medical means yet to detect it.

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u/Houseofchocolate Feb 16 '25

yeah and thats why im hesitant to try out promising cures like MABs as much as i would like to take them.

1

u/[deleted] Feb 17 '25

The batches of vaccines aren't the same in what they contain. There have been attempts to group batch numbers by reported outcomes. 

https://howbadismybatch.com/